Avascular and vascular phases in tumor cords growth
نویسندگان
چکیده
منابع مشابه
Mathematical Biomedicine and Modeling Avascular Tumor Growth
In this chapter we review existing continuum models of avascular tumor growth, explaining how they are inter-related and the biophysical insight that they provide. The models range in complexity and include one-dimensional studies of radiallysymmetric growth, and two-dimensional models of tumor invasion in which the tumor is assumed to comprise a single population of cells. We also present more...
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A mathematical and numerical model for the description of different aspects of microtumor development is presented. The model is based in the solution of a system of partial differential equations describing an avascular tumor growth. A detailed second-order numeric algorithm for solving this system is described. Parameters are swiped to cover a range of feasible physiological values. While pre...
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Tumors become especially dangerous after they induce blood vessel growth, because the new blood vessels can not only carry oxygen and nutrition that further facilitate tumor growth but also act as passages for tumor cells to spread to other sites of the body. Thus tumor growth can be divided into two phases: avascular and vascular growth. We present two simple mathematical models, 1) to underst...
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The desire to understand tumor complexity has given rise to mathematical models to describe the tumor microenvironment. We present a new mathematical model for avascular tumor growth and development that spans three distinct scales. At the cellular level, a lattice Monte Carlo model describes cellular dynamics (proliferation, adhesion, and viability). At the subcellular level, a Boolean network...
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Introduction As a tumor grows, the demand for oxygen and nutrients increases and it grows further if acquires the ability to induce angiogenesis. In this study, we aimed to present a two-dimensional continuous mathematical model for avascular tumor growth, coupled with a discrete model of angiogenesis. Materials and Methods In the avascular growth model, tumor is considered as a single mass, wh...
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ژورنال
عنوان ژورنال: Mathematical and Computer Modelling
سال: 2003
ISSN: 0895-7177
DOI: 10.1016/s0895-7177(03)00130-4